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Standardized tissue injuries were introduced, and comparative outcomes were assessed over a defined observation period

animal testing results arent accepted.6 The NEA requires three types of safety testing: the Human Repeat Insult Patch Test (HRIPT), Safety in Use (SIU), and the Cumulative Irritation Test (CIT)

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It is a C-terminal fragment of alpha-melanocyte stimulating hormone (-MSH), a naturally occurring peptide in the body that plays a crucial role in immune regulation and anti-inflammatory signaling

Interpretation was difficult because withdrawal itself can produce headache, nausea, dizziness and cardiovascular changes

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